General Information

  • ID:  hor001056
  • Uniprot ID:  NA
  • Protein name:  FMRFamide-related peptide
  • Gene name:  NA
  • Organism:  Fasciola hepatica
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GNFFRF
  • Length:  6
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T6 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Stimulate muscle contraction
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001056_AF2.pdbhor001056_ESM.pdb

Physical Information

Mass: 87624 Formula: C39H50N10O8
Absent amino acids: ACDEHIKLMPQSTVWY Common amino acids: F
pI: 10.55 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 3
Hydrophobicity: 0 Boman Index: -1168
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: -3086.67 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  9149416
  • Title:  The effects of FaRPs on the motility of isolated muscle strips from the liver fluke, Fasciola hepatica